Humira vs Cimzia
Adalimumab vs Certolizumab pegol · Comparison Guide
Quick Comparison
| Feature | Humira | Cimzia |
|---|---|---|
| Generic Name | Adalimumab | Certolizumab pegol |
| Manufacturer | AbbVie | UCB |
| Drug Class | TNF-alpha Inhibitor | TNF-alpha Inhibitor |
| Shared Conditions | RA, PsA, AS, Crohn's, Psoriasis | |
Key Differences: Humira vs Cimzia
Both are TNF inhibitors with similar approved indications. Cimzia's unique PEGylated Fab' fragment structure results in lower placental transfer, making it a preferred TNF inhibitor for women who may become pregnant. Humira has more biosimilars and longer post-marketing safety data. For most patients, the choice depends on prescriber preference, insurance formulary, and individual patient factors.
💊 Humira (Adalimumab)
- Class: TNF-alpha Inhibitor
- Manufacturer: AbbVie
- Full Humira information →
💊 Cimzia (Certolizumab pegol)
- Class: TNF-alpha Inhibitor
- Manufacturer: UCB
- Full Cimzia information →
Both are TNF inhibitors with similar approved indications. Cimzia's unique PEGylated Fab' fragment structure results in lower placental transfer, making it a preferred TNF inhibitor for women who may become pregnant. Humira has more biosimilars and longer post-marketing safety data. For most patients, the choice depends on prescriber preference, insurance formulary, and individual patient factors.
Neither Humira nor Cimzia is universally better — the right choice depends on your specific condition, disease severity, insurance formulary, and health history. Your prescriber will determine which is most appropriate based on your clinical situation. BiologicHealthPlus carries both and can help you compare your coverage and costs for either medication.
Switching between biologics is common. Your prescriber will evaluate your current treatment response and determine if a switch is appropriate. BiologicHealthPlus can coordinate the transition including prior authorization for your new medication.
Both Humira and Cimzia are covered by most commercial insurance plans, Medicare Part D, and Medicaid with prior authorization. BiologicHealthPlus handles insurance verification and prior authorization for both medications at no charge. Most insured patients pay $0–$35/month through manufacturer copay programs.
Humira and Cimzia both have high cash list prices ($4,000–$9,000/month range) but most commercially insured patients pay $0–$35/month through manufacturer savings programs. BiologicHealthPlus automatically enrolls every patient in all available savings programs at no charge.
✅ BiologicHealthPlus Carries Both Humira and Cimzia
We handle insurance verification, prior authorization, copay enrollment, and free cold-chain delivery for both medications. Contact us and we'll help you understand your options and costs.
Medical Disclaimer: This comparison is for educational purposes only. The choice between Humira and Cimzia should be made by your healthcare provider based on your specific medical history, disease severity, and individual circumstances. Last updated: July 2026.