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Entyvio (Vedolizumab)

Takeda · Anti-integrin (gut-selective) · IV infusion or Subcutaneous injection

💊 Cash / List Price (without insurance)
$5,500–$6,200/mo
WAC · Manufacturer published list price
🛡️ With Insurance + Copay Card
$0–$35/mo
Takeda Together · Most insured patients
🆓 Uninsured / PAP Eligible
Free
Income-based · Takeda Together

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About Entyvio (Vedolizumab)

Entyvio (Vedolizumab) is a Anti-integrin (gut-selective) manufactured by Takeda. Entyvio is a gut-selective integrin inhibitor that blocks the α4β7 integrin, preventing white blood cells from migrating into the gut wall and causing inflammation — with minimal systemic immune suppression.

💰 $0–$35/month for most insured patients

BiologicHealthPlus enrolls every patient in the Takeda Together program and all other available savings at no charge. Contact us to verify what you qualify for.

How Long Does Entyvio Take to Work?

Some patients see improvement within weeks; full clinical remission often takes 3–6 months.

Entyvio at a Glance

  • Generic: Vedolizumab
  • Manufacturer: Takeda
  • Drug Class: Anti-integrin (gut-selective)
  • Type: Biologic – Monoclonal Antibody
  • Route: IV infusion or Subcutaneous injection
  • Frequency: Every 8 weeks (IV maintenance)
  • Savings: Takeda Together
  • Storage: 36°F–46°F (2°C–8°C)
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FDA-Approved Uses for Entyvio

Entyvio is FDA-approved to treat the following conditions:

Dosage & Administration

Typical Entyvio Dosage

  • Route: IV infusion or Subcutaneous injection
  • Frequency: Every 8 weeks (IV maintenance)
  • Common Dose: 300 mg IV at weeks 0, 2, 6, then every 8 weeks. 108 mg subcutaneous every 2 weeks (maintenance only).

⚠️ Dosage varies by indication, age, and weight. Always follow your prescriber's instructions. Do not adjust your dose without medical guidance.

Storage & Cold-Chain Delivery

🌡️ Required Storage Temperature

36°F–46°F (2°C–8°C)

Keep in original carton. Protect from light. Do not freeze or shake.

✈️ Traveling with Entyvio

Use within 12 hours of reconstitution

Use an insulated cooler. Carry prescriber letter. Keep in carry-on luggage.

🚚 Free Cold-Chain Delivery

BiologicHealthPlus ships Entyvio in temperature-controlled packaging to all 50 states at no charge.

Learn about delivery →

Required Monitoring

Tests & Monitoring for Entyvio

  • Hepatitis B screening before starting
  • Monitor for liver injury
  • Monitor for severe hypersensitivity reactions

Your prescriber determines your monitoring schedule. BiologicHealthPlus coordinates with your provider's office on your behalf.

Insurance, Savings & Prior Authorization

🛡️ Commercial Insurance

Most commercially insured patients pay $0–$35/month through the Takeda Together program.

Insurance guide →

🆓 Patient Assistance Program

Uninsured or income-eligible patients may receive Entyvio free of charge through the Takeda Together PAP.

Check eligibility →

🏥 Medicare & Medicaid

BiologicHealthPlus works with Medicare Part B, Part D, and Medicaid plans nationwide. We verify your benefits at no charge.

Verify coverage →

✅ Prior Authorization — We Handle Everything at No Cost

BiologicHealthPlus files and manages prior authorizations for Entyvio completely free. We appeal denials, work with your prescriber, and get your medication approved as fast as possible.

Learn about prior authorization →

Entyvio by Condition

Entyvio (Vedolizumab) is FDA-approved for Ulcerative Colitis. Entyvio is a gut-selective integrin inhibitor that blocks the α4β7 integrin, preventing white blood cells from migrating into the gut wall and causing inflammation — with minimal systemic immune suppression. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Entyvio for Ulcerative Colitis.
Entyvio (Vedolizumab) is FDA-approved for Crohn's Disease. Entyvio is a gut-selective integrin inhibitor that blocks the α4β7 integrin, preventing white blood cells from migrating into the gut wall and causing inflammation — with minimal systemic immune suppression. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Entyvio for Crohn's Disease.

Frequently Asked Questions About Entyvio

Entyvio (Vedolizumab) is FDA-approved for: Ulcerative Colitis, Crohn's Disease.
The cash list price for Entyvio is approximately $5,500–$6,200/month. With commercial insurance and the Takeda Together program, most patients pay $0–$35/month. Uninsured or income-eligible patients may receive Entyvio free through patient assistance programs. BiologicHealthPlus enrolls every patient in all available savings at no charge.
Entyvio is a gut-selective integrin inhibitor that blocks the α4β7 integrin, preventing white blood cells from migrating into the gut wall and causing inflammation — with minimal systemic immune suppression.
Some patients see improvement within weeks; full clinical remission often takes 3–6 months.
Entyvio should be stored at 36°F–46°F (2°C–8°C). Use within 12 hours of reconstitution. Keep in original carton, protect from light, and do not freeze or shake.
Yes. Use an insulated travel cooler to maintain the required temperature during transit. Carry a letter from your prescriber explaining your medication, and keep Entyvio in your carry-on luggage to maintain temperature control and reduce the risk of loss or damage.
Entyvio may be covered under Medicare Part B or Part D depending on how it is administered and your specific plan. BiologicHealthPlus works with Medicare plans nationwide and will verify your coverage and help you understand your out-of-pocket costs.
Most insurance plans require prior authorization for Entyvio. BiologicHealthPlus handles the entire prior authorization process at no cost — we submit the request, gather clinical documentation, and appeal any denials on your behalf.
No FDA-approved biosimilars are currently available for Entyvio. BiologicHealthPlus will keep you informed as new options become available.
The Takeda Together program is a manufacturer-sponsored savings program for Entyvio. Most commercially insured patients qualify to pay $0–$35/month. BiologicHealthPlus enrolls every eligible patient in this and all other available savings programs at no additional charge.
Do not stop taking Entyvio without consulting your healthcare provider. Stopping suddenly may cause your condition to worsen or symptoms to return. Your provider will create a safe transition plan if you need to discontinue treatment.
Transferring to BiologicHealthPlus is simple. Upload your prescription via our website, WhatsApp, or email. We coordinate with your doctor's office, verify your insurance, enroll you in the Takeda Together program, and arrange free cold-chain delivery — usually within 1–2 business days.
Live vaccines are generally not recommended while taking immunosuppressive medications like Entyvio. Inactivated vaccines may be safe. Always speak with your healthcare provider about which vaccines are appropriate before receiving any immunization.

How Entyvio Compares to Other Medications

Entyvio and Humira are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Entyvio and Stelara are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Entyvio and Remicade are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Entyvio and Rinvoq are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Entyvio and Omvoh are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Entyvio and Simponi are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.

Lifestyle While Taking Entyvio

Moderate alcohol consumption is not specifically prohibited with Entyvio, but alcohol can affect your immune system and overall health. Discuss your habits with your healthcare provider for personalized guidance.
Many patients continue regular exercise while taking Entyvio. Staying physically active can support overall health and may complement your treatment. Ask your provider about any specific activity restrictions for your condition.
If you miss a dose, contact your healthcare provider or pharmacist for guidance. Do not double your next dose without medical advice. BiologicHealthPlus pharmacists are available 24/7 to assist you.
Some medications may interact with Entyvio. Always tell your prescriber and pharmacist about all medications, supplements, vitamins, and herbal products you take. BiologicHealthPlus reviews your medication list for potential interactions as part of our pharmacy services.

Related Resources

🛡️ Insurance & Savings 📋 Prior Authorization 🆓 Patient Assistance 🚚 Free Delivery 💊 All Medications 💬 Contact Pharmacist

🔗 Condition Guides for Entyvio

Ulcerative Colitis · Crohn's Disease

Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. Dosage information and approved indications are subject to change. Always consult your prescribing physician or pharmacist before making any treatment decisions. BiologicHealthPlus is a licensed specialty pharmacy — not a medical practice. Last reviewed: July 2026 by the BiologicHealthPlus Clinical Team.