Entyvio (Vedolizumab)
Takeda · Anti-integrin (gut-selective) · IV infusion or Subcutaneous injection
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About Entyvio (Vedolizumab)
Entyvio (Vedolizumab) is a Anti-integrin (gut-selective) manufactured by Takeda. Entyvio is a gut-selective integrin inhibitor that blocks the α4β7 integrin, preventing white blood cells from migrating into the gut wall and causing inflammation — with minimal systemic immune suppression.
💰 $0–$35/month for most insured patients
BiologicHealthPlus enrolls every patient in the Takeda Together program and all other available savings at no charge. Contact us to verify what you qualify for.
How Long Does Entyvio Take to Work?
Some patients see improvement within weeks; full clinical remission often takes 3–6 months.



Entyvio at a Glance
- Generic: Vedolizumab
- Manufacturer: Takeda
- Drug Class: Anti-integrin (gut-selective)
- Type: Biologic – Monoclonal Antibody
- Route: IV infusion or Subcutaneous injection
- Frequency: Every 8 weeks (IV maintenance)
- Savings: Takeda Together
- Storage: 36°F–46°F (2°C–8°C)
FDA-Approved Uses for Entyvio
Entyvio is FDA-approved to treat the following conditions:
Dosage & Administration
Typical Entyvio Dosage
- Route: IV infusion or Subcutaneous injection
- Frequency: Every 8 weeks (IV maintenance)
- Common Dose: 300 mg IV at weeks 0, 2, 6, then every 8 weeks. 108 mg subcutaneous every 2 weeks (maintenance only).
⚠️ Dosage varies by indication, age, and weight. Always follow your prescriber's instructions. Do not adjust your dose without medical guidance.
Storage & Cold-Chain Delivery
🌡️ Required Storage Temperature
36°F–46°F (2°C–8°C)
Keep in original carton. Protect from light. Do not freeze or shake.
✈️ Traveling with Entyvio
Use within 12 hours of reconstitution
Use an insulated cooler. Carry prescriber letter. Keep in carry-on luggage.
🚚 Free Cold-Chain Delivery
BiologicHealthPlus ships Entyvio in temperature-controlled packaging to all 50 states at no charge.
Learn about delivery →Required Monitoring
Tests & Monitoring for Entyvio
- Hepatitis B screening before starting
- Monitor for liver injury
- Monitor for severe hypersensitivity reactions
Your prescriber determines your monitoring schedule. BiologicHealthPlus coordinates with your provider's office on your behalf.
Insurance, Savings & Prior Authorization
🛡️ Commercial Insurance
Most commercially insured patients pay $0–$35/month through the Takeda Together program.
Insurance guide →🆓 Patient Assistance Program
Uninsured or income-eligible patients may receive Entyvio free of charge through the Takeda Together PAP.
Check eligibility →🏥 Medicare & Medicaid
BiologicHealthPlus works with Medicare Part B, Part D, and Medicaid plans nationwide. We verify your benefits at no charge.
Verify coverage →✅ Prior Authorization — We Handle Everything at No Cost
BiologicHealthPlus files and manages prior authorizations for Entyvio completely free. We appeal denials, work with your prescriber, and get your medication approved as fast as possible.
Learn about prior authorization →