Cimzia (Certolizumab pegol)
UCB · TNF-alpha Inhibitor · Subcutaneous injection
💊 Cash / List Price (without insurance)
$5,000–$6,000/mo
WAC · Manufacturer published list price
🛡️ With Insurance + Copay Card
$0–$5/mo
CIMplicity · Most insured patients
🆓 Uninsured / PAP Eligible
Free
Income-based · CIMplicity
🛒 Order Now — Direct from BiologicHealthPlus
Fill out the form and a BiologicHealthPlus pharmacist will contact you within 2 hours.
About Cimzia (Certolizumab pegol)
Cimzia (Certolizumab pegol) is a TNF-alpha Inhibitor manufactured by UCB. Cimzia contains a PEGylated Fab fragment that binds TNF-alpha. Its unique PEGylation increases half-life and may result in lower placental transfer — important for women of childbearing age.
⚠️ BLACK BOX WARNING
Serious infections and malignancy. Patients are at increased risk for developing serious infections. Lymphoma and other malignancies have been reported in patients treated with TNF blockers.
💰 $0–$5/month for most insured patients
BiologicHealthPlus enrolls every patient in the CIMplicity program and all other available savings at no charge. Contact us to verify what you qualify for.
How Long Does Cimzia Take to Work?
Most patients see improvement within 6–12 weeks; full benefit at 3–6 months.
Cimzia at a Glance
- Generic: Certolizumab pegol
- Manufacturer: UCB
- Drug Class: TNF-alpha Inhibitor
- Type: Biologic – PEGylated Fab Fragment
- Route: Subcutaneous injection
- Frequency: Every 2 weeks or monthly
- Savings: CIMplicity
- Storage: 36°F–46°F (2°C–8°C)
FDA-Approved Uses for Cimzia
Cimzia is FDA-approved to treat the following conditions:
Dosage & Administration
Typical Cimzia Dosage
- Route: Subcutaneous injection
- Frequency: Every 2 weeks or monthly
- Common Dose: 400 mg at weeks 0, 2, 4 (loading), then 200 mg every 2 weeks or 400 mg monthly (RA). Doses vary by indication.
⚠️ Dosage varies by indication, age, and weight. Always follow your prescriber's instructions. Do not adjust your dose without medical guidance.
Storage & Cold-Chain Delivery
🌡️ Required Storage Temperature
36°F–46°F (2°C–8°C)
Keep in original carton. Protect from light. Do not freeze or shake.
✈️ Traveling with Cimzia
Up to 14 days at room temperature (up to 77°F/25°C)
Use an insulated cooler. Carry prescriber letter. Keep in carry-on luggage.
🚚 Free Cold-Chain Delivery
BiologicHealthPlus ships Cimzia in temperature-controlled packaging to all 50 states at no charge.
Learn about delivery →Required Monitoring
Tests & Monitoring for Cimzia
- TB and hepatitis B screening
- CBC and liver function tests
- Monitor for infections
Your prescriber determines your monitoring schedule. BiologicHealthPlus coordinates with your provider's office on your behalf.
Insurance, Savings & Prior Authorization
🛡️ Commercial Insurance
Most commercially insured patients pay $0–$5/month through the CIMplicity program.
Insurance guide →🆓 Patient Assistance Program
Uninsured or income-eligible patients may receive Cimzia free of charge through the CIMplicity PAP.
Check eligibility →🏥 Medicare & Medicaid
BiologicHealthPlus works with Medicare Part B, Part D, and Medicaid plans nationwide. We verify your benefits at no charge.
Verify coverage →✅ Prior Authorization — We Handle Everything at No Cost
BiologicHealthPlus files and manages prior authorizations for Cimzia completely free. We appeal denials, work with your prescriber, and get your medication approved as fast as possible.
Learn about prior authorization →Cimzia by Condition
Cimzia (Certolizumab pegol) is FDA-approved for Rheumatoid Arthritis. Cimzia contains a PEGylated Fab fragment that binds TNF-alpha. Its unique PEGylation increases half-life and may result in lower placental transfer — important for women of childbearing age. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Cimzia for Rheumatoid Arthritis.
Cimzia (Certolizumab pegol) is FDA-approved for Psoriatic Arthritis. Cimzia contains a PEGylated Fab fragment that binds TNF-alpha. Its unique PEGylation increases half-life and may result in lower placental transfer — important for women of childbearing age. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Cimzia for Psoriatic Arthritis.
Cimzia (Certolizumab pegol) is FDA-approved for Ankylosing Spondylitis. Cimzia contains a PEGylated Fab fragment that binds TNF-alpha. Its unique PEGylation increases half-life and may result in lower placental transfer — important for women of childbearing age. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Cimzia for Ankylosing Spondylitis.
Cimzia (Certolizumab pegol) is FDA-approved for Crohn's Disease. Cimzia contains a PEGylated Fab fragment that binds TNF-alpha. Its unique PEGylation increases half-life and may result in lower placental transfer — important for women of childbearing age. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Cimzia for Crohn's Disease.
Cimzia (Certolizumab pegol) is FDA-approved for Plaque Psoriasis. Cimzia contains a PEGylated Fab fragment that binds TNF-alpha. Its unique PEGylation increases half-life and may result in lower placental transfer — important for women of childbearing age. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Cimzia for Plaque Psoriasis.
Frequently Asked Questions About Cimzia
Cimzia (Certolizumab pegol) is FDA-approved for: Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Crohn's Disease, Plaque Psoriasis.
The cash list price for Cimzia is approximately $5,000–$6,000/month. With commercial insurance and the CIMplicity program, most patients pay $0–$5/month. Uninsured or income-eligible patients may receive Cimzia free through patient assistance programs. BiologicHealthPlus enrolls every patient in all available savings at no charge.
Cimzia contains a PEGylated Fab fragment that binds TNF-alpha. Its unique PEGylation increases half-life and may result in lower placental transfer — important for women of childbearing age.
Most patients see improvement within 6–12 weeks; full benefit at 3–6 months.
Cimzia should be stored at 36°F–46°F (2°C–8°C). Up to 14 days at room temperature (up to 77°F/25°C). Keep in original carton, protect from light, and do not freeze or shake.
Yes. Use an insulated travel cooler to maintain the required temperature during transit. Carry a letter from your prescriber explaining your medication, and keep Cimzia in your carry-on luggage to maintain temperature control and reduce the risk of loss or damage.
Cimzia may be covered under Medicare Part B or Part D depending on how it is administered and your specific plan. BiologicHealthPlus works with Medicare plans nationwide and will verify your coverage and help you understand your out-of-pocket costs.
Most insurance plans require prior authorization for Cimzia. BiologicHealthPlus handles the entire prior authorization process at no cost — we submit the request, gather clinical documentation, and appeal any denials on your behalf.
No FDA-approved biosimilars are currently available for Cimzia. BiologicHealthPlus will keep you informed as new options become available.
The CIMplicity program is a manufacturer-sponsored savings program for Cimzia. Most commercially insured patients qualify to pay $0–$5/month. BiologicHealthPlus enrolls every eligible patient in this and all other available savings programs at no additional charge.
Do not stop taking Cimzia without consulting your healthcare provider. Stopping suddenly may cause your condition to worsen or symptoms to return. Your provider will create a safe transition plan if you need to discontinue treatment.
Transferring to BiologicHealthPlus is simple. Upload your prescription via our website, WhatsApp, or email. We coordinate with your doctor's office, verify your insurance, enroll you in the CIMplicity program, and arrange free cold-chain delivery — usually within 1–2 business days.
Live vaccines are generally not recommended while taking immunosuppressive medications like Cimzia. Inactivated vaccines may be safe. Always speak with your healthcare provider about which vaccines are appropriate before receiving any immunization.
How Cimzia Compares to Other Medications
Cimzia and Humira are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Cimzia and Enbrel are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Cimzia and Simponi are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Cimzia and Remicade are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Cimzia and Orencia are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Cimzia and Cosentyx are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Cimzia and Stelara are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Lifestyle While Taking Cimzia
Moderate alcohol consumption is not specifically prohibited with Cimzia, but alcohol can affect your immune system and overall health. Discuss your habits with your healthcare provider for personalized guidance.
Many patients continue regular exercise while taking Cimzia. Staying physically active can support overall health and may complement your treatment. Ask your provider about any specific activity restrictions for your condition.
If you miss a dose, contact your healthcare provider or pharmacist for guidance. Do not double your next dose without medical advice. BiologicHealthPlus pharmacists are available 24/7 to assist you.
Some medications may interact with Cimzia. Always tell your prescriber and pharmacist about all medications, supplements, vitamins, and herbal products you take. BiologicHealthPlus reviews your medication list for potential interactions as part of our pharmacy services.
Related Resources
🔗 Condition Guides for Cimzia
Rheumatoid Arthritis · Psoriatic Arthritis · Ankylosing Spondylitis · Crohn's Disease · Plaque Psoriasis
Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. Dosage information and approved indications are subject to change. Always consult your prescribing physician or pharmacist before making any treatment decisions. BiologicHealthPlus is a licensed specialty pharmacy — not a medical practice. Last reviewed: July 2026 by the BiologicHealthPlus Clinical Team.