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Stelara (Ustekinumab)

Janssen · IL-12/23 Inhibitor · Subcutaneous injection or IV infusion

💊 Cash / List Price (without insurance)
$8,000–$9,000/mo
WAC · Manufacturer published list price
🛡️ With Insurance + Copay Card
$0–$5/mo
Janssen CarePath · Most insured patients
🆓 Uninsured / PAP Eligible
Free
Income-based · Janssen CarePath

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About Stelara (Ustekinumab)

Stelara (Ustekinumab) is a IL-12/23 Inhibitor manufactured by Janssen. Stelara targets both IL-12 and IL-23, two cytokines central to the inflammatory process. By blocking both, it reduces T-cell activation and the downstream inflammatory response.

FDA-Approved Biosimilars for Stelara

Biosimilars approved for Stelara include: Wezlana, Selarsdi, Otulfi, Imuldosa. Talk to your BiologicHealthPlus pharmacist about biosimilar options and potential savings differences.

💰 $0–$5/month for most insured patients

BiologicHealthPlus enrolls every patient in the Janssen CarePath program and all other available savings at no charge. Contact us to verify what you qualify for.

How Long Does Stelara Take to Work?

Skin clearing usually begins within 4–8 weeks, with continued improvement through 12–28 weeks.

Stelara at a Glance

  • Generic: Ustekinumab
  • Manufacturer: Janssen
  • Drug Class: IL-12/23 Inhibitor
  • Type: Biologic – Monoclonal Antibody
  • Route: Subcutaneous injection or IV infusion
  • Frequency: Every 12 weeks after loading dose
  • Savings: Janssen CarePath
  • Storage: 36°F–46°F (2°C–8°C)
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FDA-Approved Uses for Stelara

Stelara is FDA-approved to treat the following conditions:

Dosage & Administration

Typical Stelara Dosage

  • Route: Subcutaneous injection or IV infusion
  • Frequency: Every 12 weeks after loading dose
  • Common Dose: 45 mg or 90 mg (weight-based) at weeks 0 and 4, then every 12 weeks (psoriasis).

⚠️ Dosage varies by indication, age, and weight. Always follow your prescriber's instructions. Do not adjust your dose without medical guidance.

Storage & Cold-Chain Delivery

🌡️ Required Storage Temperature

36°F–46°F (2°C–8°C)

Keep in original carton. Protect from light. Do not freeze or shake.

✈️ Traveling with Stelara

Up to 30 days at up to 86°F (30°C)

Use an insulated cooler. Carry prescriber letter. Keep in carry-on luggage.

🚚 Free Cold-Chain Delivery

BiologicHealthPlus ships Stelara in temperature-controlled packaging to all 50 states at no charge.

Learn about delivery →

Required Monitoring

Tests & Monitoring for Stelara

  • Tuberculosis and hepatitis B screening before starting
  • Assess for skin cancer risk periodically
  • Monitor for infections

Your prescriber determines your monitoring schedule. BiologicHealthPlus coordinates with your provider's office on your behalf.

Insurance, Savings & Prior Authorization

🛡️ Commercial Insurance

Most commercially insured patients pay $0–$5/month through the Janssen CarePath program.

Insurance guide →

🆓 Patient Assistance Program

Uninsured or income-eligible patients may receive Stelara free of charge through the Janssen CarePath PAP.

Check eligibility →

🏥 Medicare & Medicaid

BiologicHealthPlus works with Medicare Part B, Part D, and Medicaid plans nationwide. We verify your benefits at no charge.

Verify coverage →

✅ Prior Authorization — We Handle Everything at No Cost

BiologicHealthPlus files and manages prior authorizations for Stelara completely free. We appeal denials, work with your prescriber, and get your medication approved as fast as possible.

Learn about prior authorization →

Stelara by Condition

Stelara (Ustekinumab) is FDA-approved for Plaque Psoriasis. Stelara targets both IL-12 and IL-23, two cytokines central to the inflammatory process. By blocking both, it reduces T-cell activation and the downstream inflammatory response. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Stelara for Plaque Psoriasis.
Stelara (Ustekinumab) is FDA-approved for Psoriatic Arthritis. Stelara targets both IL-12 and IL-23, two cytokines central to the inflammatory process. By blocking both, it reduces T-cell activation and the downstream inflammatory response. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Stelara for Psoriatic Arthritis.
Stelara (Ustekinumab) is FDA-approved for Crohn's Disease. Stelara targets both IL-12 and IL-23, two cytokines central to the inflammatory process. By blocking both, it reduces T-cell activation and the downstream inflammatory response. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Stelara for Crohn's Disease.
Stelara (Ustekinumab) is FDA-approved for Ulcerative Colitis. Stelara targets both IL-12 and IL-23, two cytokines central to the inflammatory process. By blocking both, it reduces T-cell activation and the downstream inflammatory response. Your prescriber will determine the appropriate dose and monitoring schedule based on your specific condition and health history. BiologicHealthPlus can assist with insurance verification, prior authorization, and free cold-chain delivery of Stelara for Ulcerative Colitis.

Frequently Asked Questions About Stelara

Stelara (Ustekinumab) is FDA-approved for: Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, Ulcerative Colitis.
The cash list price for Stelara is approximately $8,000–$9,000/month. With commercial insurance and the Janssen CarePath program, most patients pay $0–$5/month. Uninsured or income-eligible patients may receive Stelara free through patient assistance programs. BiologicHealthPlus enrolls every patient in all available savings at no charge.
Stelara targets both IL-12 and IL-23, two cytokines central to the inflammatory process. By blocking both, it reduces T-cell activation and the downstream inflammatory response.
Skin clearing usually begins within 4–8 weeks, with continued improvement through 12–28 weeks.
Stelara should be stored at 36°F–46°F (2°C–8°C). Up to 30 days at up to 86°F (30°C). Keep in original carton, protect from light, and do not freeze or shake.
Yes. Use an insulated travel cooler to maintain the required temperature during transit. Carry a letter from your prescriber explaining your medication, and keep Stelara in your carry-on luggage to maintain temperature control and reduce the risk of loss or damage.
Stelara may be covered under Medicare Part B or Part D depending on how it is administered and your specific plan. BiologicHealthPlus works with Medicare plans nationwide and will verify your coverage and help you understand your out-of-pocket costs.
Most insurance plans require prior authorization for Stelara. BiologicHealthPlus handles the entire prior authorization process at no cost — we submit the request, gather clinical documentation, and appeal any denials on your behalf.
FDA-approved biosimilars for Stelara include: Wezlana, Selarsdi, Otulfi, Imuldosa. Biosimilars are FDA-approved alternatives that may offer different savings options. Talk to your BiologicHealthPlus pharmacist about whether a biosimilar is appropriate for you.
The Janssen CarePath program is a manufacturer-sponsored savings program for Stelara. Most commercially insured patients qualify to pay $0–$5/month. BiologicHealthPlus enrolls every eligible patient in this and all other available savings programs at no additional charge.
Do not stop taking Stelara without consulting your healthcare provider. Stopping suddenly may cause your condition to worsen or symptoms to return. Your provider will create a safe transition plan if you need to discontinue treatment.
Transferring to BiologicHealthPlus is simple. Upload your prescription via our website, WhatsApp, or email. We coordinate with your doctor's office, verify your insurance, enroll you in the Janssen CarePath program, and arrange free cold-chain delivery — usually within 1–2 business days.
Live vaccines are generally not recommended while taking immunosuppressive medications like Stelara. Inactivated vaccines may be safe. Always speak with your healthcare provider about which vaccines are appropriate before receiving any immunization.

How Stelara Compares to Other Medications

Stelara and Humira are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Stelara and Skyrizi are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Stelara and Tremfya are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Stelara and Entyvio are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Stelara and Rinvoq are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Stelara and Cosentyx are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Stelara and Ilumya are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.
Stelara and Bimzelx are both used in autoimmune or inflammatory conditions but differ in mechanism of action, dosing schedule, administration route, approved indications, and safety profiles. Your prescriber will help determine which medication is most appropriate for your specific condition, health history, and insurance coverage. BiologicHealthPlus carries both — contact us to check your eligibility for savings programs for either medication.

Lifestyle While Taking Stelara

Moderate alcohol consumption is not specifically prohibited with Stelara, but alcohol can affect your immune system and overall health. Discuss your habits with your healthcare provider for personalized guidance.
Many patients continue regular exercise while taking Stelara. Staying physically active can support overall health and may complement your treatment. Ask your provider about any specific activity restrictions for your condition.
If you miss a dose, contact your healthcare provider or pharmacist for guidance. Do not double your next dose without medical advice. BiologicHealthPlus pharmacists are available 24/7 to assist you.
Some medications may interact with Stelara. Always tell your prescriber and pharmacist about all medications, supplements, vitamins, and herbal products you take. BiologicHealthPlus reviews your medication list for potential interactions as part of our pharmacy services.

Related Resources

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Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. Dosage information and approved indications are subject to change. Always consult your prescribing physician or pharmacist before making any treatment decisions. BiologicHealthPlus is a licensed specialty pharmacy — not a medical practice. Last reviewed: July 2026 by the BiologicHealthPlus Clinical Team.