Stelara (Ustekinumab)
Janssen · IL-12/23 Inhibitor · Subcutaneous injection or IV infusion
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About Stelara (Ustekinumab)
Stelara (Ustekinumab) is a IL-12/23 Inhibitor manufactured by Janssen. Stelara targets both IL-12 and IL-23, two cytokines central to the inflammatory process. By blocking both, it reduces T-cell activation and the downstream inflammatory response.
FDA-Approved Biosimilars for Stelara
Biosimilars approved for Stelara include: Wezlana, Selarsdi, Otulfi, Imuldosa. Talk to your BiologicHealthPlus pharmacist about biosimilar options and potential savings differences.
💰 $0–$5/month for most insured patients
BiologicHealthPlus enrolls every patient in the Janssen CarePath program and all other available savings at no charge. Contact us to verify what you qualify for.
How Long Does Stelara Take to Work?
Skin clearing usually begins within 4–8 weeks, with continued improvement through 12–28 weeks.



Stelara at a Glance
- Generic: Ustekinumab
- Manufacturer: Janssen
- Drug Class: IL-12/23 Inhibitor
- Type: Biologic – Monoclonal Antibody
- Route: Subcutaneous injection or IV infusion
- Frequency: Every 12 weeks after loading dose
- Savings: Janssen CarePath
- Storage: 36°F–46°F (2°C–8°C)
FDA-Approved Uses for Stelara
Stelara is FDA-approved to treat the following conditions:
Dosage & Administration
Typical Stelara Dosage
- Route: Subcutaneous injection or IV infusion
- Frequency: Every 12 weeks after loading dose
- Common Dose: 45 mg or 90 mg (weight-based) at weeks 0 and 4, then every 12 weeks (psoriasis).
⚠️ Dosage varies by indication, age, and weight. Always follow your prescriber's instructions. Do not adjust your dose without medical guidance.
Storage & Cold-Chain Delivery
🌡️ Required Storage Temperature
36°F–46°F (2°C–8°C)
Keep in original carton. Protect from light. Do not freeze or shake.
✈️ Traveling with Stelara
Up to 30 days at up to 86°F (30°C)
Use an insulated cooler. Carry prescriber letter. Keep in carry-on luggage.
🚚 Free Cold-Chain Delivery
BiologicHealthPlus ships Stelara in temperature-controlled packaging to all 50 states at no charge.
Learn about delivery →Required Monitoring
Tests & Monitoring for Stelara
- Tuberculosis and hepatitis B screening before starting
- Assess for skin cancer risk periodically
- Monitor for infections
Your prescriber determines your monitoring schedule. BiologicHealthPlus coordinates with your provider's office on your behalf.
Insurance, Savings & Prior Authorization
🛡️ Commercial Insurance
Most commercially insured patients pay $0–$5/month through the Janssen CarePath program.
Insurance guide →🆓 Patient Assistance Program
Uninsured or income-eligible patients may receive Stelara free of charge through the Janssen CarePath PAP.
Check eligibility →🏥 Medicare & Medicaid
BiologicHealthPlus works with Medicare Part B, Part D, and Medicaid plans nationwide. We verify your benefits at no charge.
Verify coverage →✅ Prior Authorization — We Handle Everything at No Cost
BiologicHealthPlus files and manages prior authorizations for Stelara completely free. We appeal denials, work with your prescriber, and get your medication approved as fast as possible.
Learn about prior authorization →Stelara by Condition
Frequently Asked Questions About Stelara
How Stelara Compares to Other Medications
Lifestyle While Taking Stelara
Related Resources
🔗 Condition Guides for Stelara
Plaque Psoriasis · Psoriatic Arthritis · Crohn's Disease · Ulcerative Colitis