Rinvoq (Upadacitinib)
AbbVie · JAK Inhibitor · Oral tablet (once daily)
💊 Cash / List Price (without insurance)
$5,200/mo
WAC · Manufacturer published list price
🛡️ With Insurance + Copay Card
$0–$35/mo
myAbbVie Assist · Most insured patients
🆓 Uninsured / PAP Eligible
Free
Income-based · myAbbVie Assist
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Rinvoq at a Glance
- Generic: Upadacitinib
- Manufacturer: AbbVie
- Mechanism: JAK Inhibitor
- Drug Class: Targeted Synthetic DMARD (oral)
- Route: Oral tablet (once daily)
- Frequency: Once daily
- Savings Program: myAbbVie Assist
About Rinvoq
Rinvoq (upadacitinib) is a JAK inhibitor manufactured by AbbVie. Unlike injectable biologics, Rinvoq is taken as an oral once-daily tablet. It inhibits Janus kinase enzymes involved in inflammatory signaling.
FDA-Approved Indications
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Ankylosing Spondylitis
- Crohn's Disease
- Ulcerative Colitis
- Atopic Dermatitis
💰 $0–$35/month for most insured patients
BiologicHealthPlus enrolls every patient in the myAbbVie Assist program and all other available savings at no charge. Contact us to see what you qualify for.
Frequently Asked Questions
Rinvoq is FDA-approved for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and moderate-to-severe atopic dermatitis.
Rinvoq is a targeted synthetic DMARD (JAK inhibitor), not a traditional biologic. However, it is often prescribed alongside or instead of biologics for certain autoimmune conditions.
Through the myAbbVie Assist program, most insured patients pay $0–$35/month.
Comparisons
Rinvoq and Humira are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Skyrizi are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Xeljanz are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Otezla are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Cosentyx are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Tremfya are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Taltz are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Enbrel are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Orencia are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Rinvoq and Cimzia are both used in inflammatory conditions but differ in mechanism, dosing, administration route, and approved indications. Your healthcare provider can help determine which medication is most appropriate for your specific situation.
Lifestyle
Moderate alcohol consumption is not specifically prohibited with Rinvoq, but alcohol can affect your immune system and overall health. Discuss your habits with your healthcare provider.
Many patients continue regular exercise while taking Rinvoq. Staying active may support your overall health. Ask your provider about any activity restrictions specific to your condition.
No specific dietary restrictions are required for Rinvoq. A balanced, nutritious diet supports immune health and may complement your treatment. Consult your provider if you have concerns.
Some antibiotics may interact with immunosuppressive medications. Always inform your prescriber and pharmacist of any antibiotics you are taking while on Rinvoq.
Certain supplements may interact with Rinvoq or affect your immune response. Tell your healthcare provider and pharmacist about all supplements you take.
Some herbal products can interact with biologics or alter immune function. Disclose all herbal medicines to your provider before starting or while taking Rinvoq.
Some patients report changes in sleep while on biologic therapy. If you experience sleep disturbances while taking Rinvoq, discuss them with your healthcare provider.
Some patients notice mood changes while on biologic therapy. Controlling your underlying condition may also affect how you feel. Talk to your provider if you notice mood or mental health changes.
Live vaccines are generally not recommended while taking Rinvoq. Speak with your healthcare provider about which vaccines are safe and appropriate for you before receiving any immunizations.
Not smoking, maintaining a healthy weight, staying physically active, following your prescribed schedule, and attending regular check-ups may all support better outcomes with Rinvoq.
Travel & Storage
Rinvoq should be stored at room temperature away from heat, moisture, and direct light. Keep it in its original container with the cap tightly closed.
No. Rinvoq is an oral medication stored at room temperature. Check the prescribing information for the specific recommended temperature range.
Freezing is not applicable to Rinvoq as it is an oral medication. Store it at room temperature as directed.
Rinvoq is designed to be stored at room temperature. Follow the storage conditions on the label and avoid extreme heat or humidity.
Yes. Rinvoq is an oral medication and straightforward to travel with. Keep it in its original container and carry it in your carry-on luggage.
Yes. Oral prescription medications are permitted through airport security. Carry the original pharmacy label to assist identification if needed.
International shipping regulations for prescription medications vary by country. Contact your specialty pharmacy for guidance before any international shipment.
It is generally safer to carry prescription medications in your carry-on luggage to reduce the risk of loss or damage.
A letter from your prescriber explaining your medication is recommended for international travel to assist with customs and security.
Contact your healthcare provider and specialty pharmacy as soon as possible. They can help arrange an emergency supply or advise on next steps.
Patient Education
Take Rinvoq exactly as prescribed by your healthcare provider. Follow the dosing schedule and any specific instructions on your prescription label.
If you miss a dose, take it as soon as you remember unless it is close to the time of your next scheduled dose. Do not double up. Contact your pharmacist if you are unsure.
Your healthcare provider will determine which baseline tests are needed based on your medical history and the condition being treated.
Monitoring frequency depends on your condition and health status. Your provider will establish an appropriate schedule.
Do not stop Rinvoq without consulting your healthcare provider. Stopping without guidance could affect disease management.
Contact your provider if you experience signs of infection, unexpected side effects, worsening symptoms, or any other concerns about your treatment.
Report side effects to your healthcare provider promptly. For severe reactions seek emergency care immediately.
Your healthcare provider, pharmacist, the manufacturer's official website, and FDA prescribing information are reliable sources.
Ask about expected benefits, potential risks, how long until results may appear, what to do if you miss a dose, and interactions with other medications or supplements.
Your provider will monitor your response to treatment over time and may adjust your dose or schedule as needed. Regular check-ins are an important part of managing your condition.
Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. Always consult your prescribing physician or pharmacist before making any treatment decisions. BiologicHealthPlus is a licensed specialty pharmacy — not a medical practice.