Actemra vs Kevzara
Tocilizumab vs Sarilumab · Comparison Guide
Quick Comparison
| Feature | Actemra | Kevzara |
|---|---|---|
| Generic Name | Tocilizumab | Sarilumab |
| Manufacturer | Genentech | Sanofi/Regeneron |
| Drug Class | IL-6 Receptor Inhibitor | IL-6 Receptor Inhibitor |
| Shared Conditions | Rheumatoid Arthritis | |
Key Differences: Actemra vs Kevzara
Both are IL-6 receptor inhibitors for RA with similar mechanisms. Actemra (tocilizumab) is available in both IV and subcutaneous formulations and is approved for more indications (GCA, JIA). Kevzara (sarilumab) is subcutaneous only and approved for RA. Actemra has a longer clinical track record and more real-world data. Both require CBC and lipid monitoring.
💊 Actemra (Tocilizumab)
- Class: IL-6 Receptor Inhibitor
- Manufacturer: Genentech
- Full Actemra information →
💊 Kevzara (Sarilumab)
- Class: IL-6 Receptor Inhibitor
- Manufacturer: Sanofi/Regeneron
- Full Kevzara information →
Both are IL-6 receptor inhibitors for RA with similar mechanisms. Actemra (tocilizumab) is available in both IV and subcutaneous formulations and is approved for more indications (GCA, JIA). Kevzara (sarilumab) is subcutaneous only and approved for RA. Actemra has a longer clinical track record and more real-world data. Both require CBC and lipid monitoring.
Neither Actemra nor Kevzara is universally better — the right choice depends on your specific condition, disease severity, insurance formulary, and health history. Your prescriber will determine which is most appropriate based on your clinical situation. BiologicHealthPlus carries both and can help you compare your coverage and costs for either medication.
Switching between biologics is common. Your prescriber will evaluate your current treatment response and determine if a switch is appropriate. BiologicHealthPlus can coordinate the transition including prior authorization for your new medication.
Both Actemra and Kevzara are covered by most commercial insurance plans, Medicare Part D, and Medicaid with prior authorization. BiologicHealthPlus handles insurance verification and prior authorization for both medications at no charge. Most insured patients pay $0–$35/month through manufacturer copay programs.
Actemra and Kevzara both have high cash list prices ($4,000–$9,000/month range) but most commercially insured patients pay $0–$35/month through manufacturer savings programs. BiologicHealthPlus automatically enrolls every patient in all available savings programs at no charge.
✅ BiologicHealthPlus Carries Both Actemra and Kevzara
We handle insurance verification, prior authorization, copay enrollment, and free cold-chain delivery for both medications. Contact us and we'll help you understand your options and costs.
Medical Disclaimer: This comparison is for educational purposes only. The choice between Actemra and Kevzara should be made by your healthcare provider based on your specific medical history, disease severity, and individual circumstances. Last updated: July 2026.